Department of Microbiology & Immunology
Albert Einstein College of Medicine
Publications
For an up-to-date list of our lab’s work: Pubmed
Libusha Kelly’s Google Scholar page
Recent notable publications:
Viral ecology
Flamholz Z, Biller S, Kelly L. Large language models improve annotation of viral proteins, 02 May 2023, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-2852098/v1]. In press, Nature Microbiology.
Kauffman KM†, Chang WK†, Brown JM, Hussain FA, Yang J, Polz MF*, Kelly L*. Resolving the structure of phage-bacteria interactions in the context of natural diversity. Nature Communications 2022 Jan 18;13(1):372. PMID: 35042853; PMCID: PMC8766483.
Yang JY, Fang W, Miranda-Sanchez F, Brown JM, Kauffman KM, Acevero CM, Bartel DP, Polz MF*, Kelly L*. Degradation of host translational machinery drives tRNA acquisition in viruses. Cell Systems 2021 Aug 18;12(8):771-779.e5. PMID: 34143976; PMCID: PMC8826309.
Kauffman KM, Hussain FA, Yang J, Arevalo P, Brown JM, Chang WK, VanInsberghe D, Elsherbini J, Sharma RS, Cutler MB, Kelly L*, Polz MF*. A major lineage of non-tailed dsDNA viruses as unrecognized killers of marine bacteria. Nature. 2018 Feb 1;554(7690):118-122. doi: 10.1038/nature25474. PubMed PMID: 29364876.
Microbiome drug metabolism
Wolfson SJ, Hitchings R, Peregrina K, Cohen Z, Khan S, Yilmaz T, Malena M, Goluch ED, Augenlicht L, Kelly L. Bacterial hydrogen sulfide drives cryptic redox chemistry in gut microbial communities. Nat Metab. 2022 Oct;4(10):1260-1270. doi: 10.1038/s42255-022-00656-z. Epub 2022 Oct 20. PMID: 36266544.
Guthrie L, Wolfson S, Kelly L. The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs. Elife. 2019 Jun 11;8. doi: 10.7554/eLife.42866. PubMed PMID: 31184303; PMCID:PMC6559788.
Guthrie L, Gupta S, Daily J, Kelly L. Human microbiome signatures of differential colorectal cancer drug metabolism. NPJ Biofilms Microbiomes. 2017 Nov 1;3:27. doi: 10.1038/s41522-017-0034-1. eCollection 2017. PMID:29104759; PMCID: PMC5665930
(†= co-first author; *=co-corresponding author).